Reduci del Vaccino : Esperienze, imprevisti o quant'altro.

[Musoita]

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DEFINE_ME

Si infatti :

Conclusions

A small minority of fully vaccinated BNT162b2 recipients might still develop severe SARS-CoV-2 infection despite the vaccine's high effectiveness, with need for in-patient care. This representative cohort of hospitalized patients is characterized by older age, high rate of co-morbidities predisposing for progression to severe COVID-19 and a high rate of immunosuppression. The outcome of these patients was similar to that of non-vaccinated hospitalized COVID-19 patients. Additional prospective longitudinal studies are urgently needed to identify predictors for vaccine breakthrough infection and simple correlates of vaccine protection, to enable identification of individuals at higher risk, who would require continued strict precautions, and possibly repeated active vaccination or other prophylactic measures, such as passive vaccination. Furthermore, indirect protection of vulnerable individuals is best achieved by mass vaccination leading to herd immunity.

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